1. Purpose : This study investigated gender, religious affiliation, institution of learning and academic level as factors predicting sexual risk susceptibility among university undergraduates drawn from two Univer - sities in South-Western Nigeria. 2. Methods : Using an ex-post facto survey research design and random sampling methods, a total of 320 participants were selected for the study. 118 (36.9%) were male, 202 (63.1%) were female. Validated scale was used for data collection. Four hypotheses were stated, two of which were analyzed using t-test of independent means, while the remaining two were analyzed using a univariate analysis of variance.